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To help you better understand ankylosing spondylitis, this article will highlight key facts and statistics about the condition, including who is at risk, its effects on mortality, and screening and early detection. Ankylosing Spondylitis Overview AS is a form of axial spondyloarthritis that affects the joints of the spine, chest, and pelvis. It is also an autoimmune disease where the immune system malfunctions and attacks healthy tissues. The other type of axial spondylarthritis is non-radiographic axial spondyloarthritis (nr-AxSpA)....

That revelation shines a spotlight on the hot—and sometimes murky—market for HGH. Touted as a wonder drug that builds muscle, sheds fat and restores youth, HGH has grown into a multibillion-dollar worldwide business, by some estimates. The only problem is, it’s not always a legal one. Though growth hormone has certain uses approved by the Food and Drug Administration, these don’t include anti-aging therapy, bodybuilding or athletic enhancement. Just last month, Sylvester Stallone was charged by Australian authorities with illegally importing 48 vials of the stuff....

It’s been 16 years since Hathaway played Andy Sachs in the cult movie opposite Meryl Streep, whose character, Priestly, a powerful and intimidating editor-in-chief, was not so loosely based on Vogue magazine editor Wintour. So when Hathaway and Wintour were photographed side by side at the New York fashion show on Wednesday, fans of The Devil Wears Prada just about lost their minds. What’s more, Hathaway 39, eerily resembled her movie character, with the same haircut and a brown ensemble similar to the one she wore in the film....

The latest crater was found by Oleg Shabalin, head of the nearby Gyda village. He reported the find, thinking it may have formed through an explosive release of methane as others like this are known to develop. These funnels of gases are “increasingly common throughout the tundra zone of Russia,” he told The Siberian Times. However, scientists have said this depression, which is about 65 feet deep but filled with sludge, likely formed as a result of warm temperatures, with ice trapped in the permafrost melting and causing the soil to collapse....

Set in a military-guarded desert location, the initial image appeared to hint at a Half-Life-style vehicle/shooter hybrid. Bleszinski followed up that teaser with a second, partially obscured clue some days later, this time showcasing a futuristic basketball-like variant. With the game’s action occurring just off-screen, viewers are instead treated to an array of 10ft bionic benchwarmers. From piston-like legs, to powerful hidden jetpacks, the players’ augmented appendages appeared to confirm the title as a straight up sci-fi experience....

Officers conducting security checks at the George Beto Unit in Tennessee Colony in the early morning hours of March 11 saw smoke coming from an inmate’s cell, Robert Hurst, a public information officer for the Texas Department of Criminal Justice, confirmed to Newsweek. “Officers initiated an emergency response and extinguished the fire that was set by the inmate,” Hurst said. The inmate, Damien Bryant, was found unresponsive in his cell....

Police in the town of Harlingen arrested a man early Saturday morning who posed to be an “imminent threat” at a Walmart in that town. The Harlingen Police Department released a statement, calling it a “terroristic threat arrest.” Police in Harlingen posted a statement on its Facebook page that “investigation officers learned that a male subject had used a social media site to post up an imminent threat that was to occur at the Wal-Mart in Harlingen on a specific date....

I got into the Anthem VIP demo a day late. It didn’t (and still doesn’t, but more on that in a bit) seem like a game I need to play on Day 1 and also, as a general rule, I don’t pre-order games unless publishers really sweeten the deal for me (Yakuza 6: The Song of Life included Yakuza 0 so that was a no-brainer). So, I didn’t pre-order Anthem and, therefore, just assumed I didn’t have access to the early demo....

Taking to Twitter, BioWare’s head of live services Chad Robertson attempted to provide some clarity on the current Anthem situation and confirmed that both BioWare’s Austin and Edmonton studios are dedicated to continuing to improve and fix the current game. In an effort to not overpromise going forward, the studio plans to only share updates on what’s coming when things are near completion. Lead producer Michael Gamble also jumped in on the conversation to echo that BioWare’s support and commitment to Anthem haven’t changed throughout all of this developer movement....

He looked the part of a top-five NBA player in his LA debut Saturday, as evidenced by these dunks against the Warriors, two of his five in the first quarter. TRADE RUMORS: Latest news on Russell and others “I haven’t played in awhile, so I was just trying to do the little things and the ball just kind of ended up in my hands. So I just tried to get up and dunk it and get myself going,” Davis (22 points, 10 rebounds in 18 minutes) told reporters after the game, per NBA....

Davis has proven to be a jack of all trades, dominating on defense and holding up more than his end on offense. On Tuesday, in Team USA’s game against New Zealand, Davis flashed his elite athleticism. MORE: Spurs work out Earl Clark | Celtics not trading Rondo | Trade targets With so many athletes, the alley-oop lobs have been in abundance for Team USA, with most of them being thrown in Davis’ direction....

On the court, he’s absolutely electrifying. He has already delivered Dunk of the Year candidates, game-winning shots and smashed some records along the way, proving himself well-worthy of his No. 1 overall selection in the 2020 NBA Draft – and he’s only 20-years-old. Off the court, he’s glowingly charismatic and confident, making for an enjoyably hilarious soundbite any time he has a microphone in front of him. Simply put, Anthony Edwards has become the best quote in the NBA, and every press conference and interview turns into must-see or must-read material....

“Who?” MORE: NFL Mock Draft 2017: Who do Chargers take? True, Lynn isn’t the trendy candidate that Kyle Shanahan is, nor does he have the pedigree that Sean McVay brings to the Rams. Lynn was an NFL offensive coordinator for less than a full season, and he lost his only game as the Bills’ interim head coach to the hapless Jets. Before taking over as Buffalo’s OC in Week 3 of this season, he looked like a career running backs coach, having served in that role from 2003-14 for a collection of teams....

Two important notes to remember as you read this … First, this isn’t Sporting News opinion. This is strictly a by-the-numbers position-by-position look at the worst everyday players in baseball, using Fangraphs.com’s WAR calculation. WAR isn’t a perfect metric, but it’s considered the best way to look at a player’s complete overall contribution (hitting/fielding/base running/etc.). And, second: We are not saying these are the worst players in baseball. The worst players in the majors don’t see the field very often....

Fortnite addiction and game addiction in general has caused people to create petitions to ban Fortnite and other games. There’s really no chance of those petitions being taken seriously by video game developers, so it seems frustrated spouses or parents may be looking for other solutions, and the Anti-Gaming Spray could very well be something that they consider. Alternatively, it’s easy to see some people using Anti-Gaming Spray just to play pranks on people....

Nearly two dozen residents gathered for the commissioner meeting to support the anti-mask mandate resolution that accuses Mills of interfering with citizen liberties by requiring the use of facial coverings in public. The resolution, which was introduced by County Commissioner Isaiah Lary, says that all citizens, businesses and visitors of Androscoggin County should be “free to wear or not wear masks” in accordance with their own preference. The resolution also claims that there is “scant evidence” to support that facial coverings effectively prevent the spread of COVID-19, despite scientific data from public health experts and the Centers of Disease Control and Prevention (CDC) that say they do....

Charles III became king of the United Kingdom, and 14 other countries known as the Commonwealth realms, on Thursday when Queen Elizabeth II passed away aged 96. On Saturday, Charles was formally declared king by the Accession Council, a body dating back to England’s early medieval history, at St. James’s Palace in London. The principal proclamation was read out by David White, confirming the new monarch, though a date has yet to be set for Charles’ coronation....

Shortly after Dugina was killed in a car bombing on the outskirts of Moscow, former Russian State Deputy Ilya Ponomarev claimed that the assassination was organized by the NRA. Ponomarev also alleged that she and her father, Alexander Dugin, an influential ally of Russian President Vladimir Putin, were both targets of the attack. Ponomarev’s claims could not be verified by Newsweek. On Monday, after a brief investigation, Russia’s FSB security services accused Ukraine’s secret services and a female Ukrainian citizen of plotting Dugina’s killing....